Two of the game’s most highly regarded offensive minds will be in action on Monday Night Football when Kyle Shanahan and Sean McVay lead the 49ers and Rams into battle. The Niners have dominated this series of late, winning the past four meetings, but the Rams opened as four-point road favorites and provide the higher-ceiling plays for our FanDuel single-game DFS lineup.
Here are the key scoring settings for FanDuel’s single-game contests: The point total for the “MVP” is multiplied by 1.5, but he doesn’t cost any additional money like the “Captain” in DraftKings Showdown contests. FanDuel’s default scoring is half-point PPR and four-point passing TDs, and there are no bonuses for 300-yard/100-yard games like on DraftKings.
MORE FD SINGLE GAME: How to win a FanDuel single-game contest
FanDuel Single Game DFS Picks: Rams vs. 49ers
$60,000 budget, need at least one player from each team
MVP (1.5x points): WR Cooper Kupp, Rams ($16,000)
Kupp’s 15.0 FanDuel points last week qualified as a “down” game, and it was his lowest output since Week 5 against the Seahawks. New acquisition Odell Beckham Jr. will command his share of targets in time, but until he gets comfortable in his new digs, Kupp may be tasked with picking up the slack left after Robert Woods’ season-ending knee injury. It’s reasonable to expect another 10-plus targets for Kupp.
FLEX: QB Matthew Stafford, Rams ($17,000)
In the three games leading up to Stafford’s Week 9 stumble against the Titans, he averaged 25.53 FD points. The 49ers have had the Rams’ number in recent meetings, but they haven’t had Stafford in those contests. The loss of Woods hurts, but if Stafford can generate a connection with Beckham, he should be able to exploit an underachieving Niners defense.
MORE MNF: DK lineup
FLEX: RB Elijah Mitchell, 49ers ($11,500)
Mitchell has been removed from the injury report, suggesting he’s completely past the rib ailment that he’s been playing through. An even more exciting development is the five targets he received last week. He caught all five for 43 yards, offering a glimpse of what he can do in the passing game. Mitchell has scored 16.7, 19.7, and 10.4 FD points, respectively, over the past three weeks, and another good performance will be on the menu on Monday night.
FLEX: WR Van Jefferson, Rams ($8,000)
Jefferson continues to quietly piece together a strong sophomore campaign, and while Beckham will eventually — and presumably — assume full control of WR2 duties, Jefferson will be leaned on more heavily until OBJ is full up to speed. He’s finished with 10-plus FD points on four occasions and has totaled 20 targets across his past three contests. He’s averaging 16.0 yards per catch and could deliver a healthy point total with another six-to-eight looks in the passing game.
FLEX: WR Brandon Aiyuk, 49ers ($7,500)
Aiyuk has methodically worked his way back into the offense, and he delivered his best performance last week against the Cardinals. The second-year receiver turned eight targets into a 6-89-1 line, good for a season-high 15.7 FD points. If Aiyuk is truly back on track, it will be the first time we get to see the “YAC Bros” at full strength. If the Rams prioritize slowing tight end George Kittle and wide receiver Deebo Samuel, Aiyuk may face some softer matchups and coverages to exploit.