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Week 6 of NFL action concludes on “Monday Night Football” with a meeting between the Bills and Titans in Nissan Stadium in Nashville, Tenn.
Buffalo appears to be the best team in the league this year, claiming not only a top-six offense (410.4 yards per game) but also the No. 1 defense, surrendering just 251.8 yards per contest. The next-closest team in that category is Cleveland, which gives up 307.7 yards a game.
Buffalo is riding high behind quarterback Josh Allen, who has 288 rushing yards and two scores on top of his 1,370 passing yards and 12 touchdowns. The defense, meanwhile, has forced a league-high 15 turnovers for a plus-11 differential this season.
That said, the Titans have the last victory in this series, beating the Bills handily in 2020, 42-26. In that matchup, they limited eventual 2,000-yard rusher Derrick Henry to just 57 yards, though he did make a highlight reel-worthy play when he stiff-armed Josh Norman into oblivion. How will Henry, who leads the league in carries (142), yards (640) and rushing touchdowns (seven) in 2021, perform against Buffalo?
Sporting News is tracking live scoring updates and highlights from Bills vs. Titans on “Monday Night Football.” Follow for complete results from the NFL Week 6 game.
MORE: Watch Bills vs. Titans live on fuboTV (7-day free trial)
Bills vs. Titans score
| Q1 | Q2 | Q3 | Q4 | F | |
| Bills | — | — | — | — | — |
| Titans | — | — | — | — | — |
Bills vs. Titans live updates, highlights from Monday Night Football
Live updates will begin around kickoff at 8:15 p.m. ET.
Bills vs. Titans start time
- Date: Monday, Oct. 18
- Kickoff: 8:15 p.m. ET
The Bills-Titans matchup will kick off at 8:15 p.m. ET at Nissan Stadium in Nashville, Tenn. All “Monday Night Football” games in 2021 are scheduled to begin at 8:15 p.m. ET.
How to watch Monday Night Football
Week 6 will end with the Bills facing the Titans on “Monday Night Football,” with Steve Levy set to handle play-by-play and Brian Griese and Louis Riddick providing analysis on the ESPN broadcast. Lisa Salters will be the sideline reporter for the game while former NFL referee John Parry will be the rules analyst.
This will not be a ManningCast, as Peyton and Eli Manning will be off for the third straight week. They’ll return to ESPN2 for Week 7 with the Seahawks taking on the Saints on “Monday Night Football.”
Streaming audiences can watch the game on the ESPN app, using ESPN+ or by using fuboTV, which offers a 7-day free trial.
‘Monday Night Football’ schedule 2021
| Week | Date | Matchup |
| Week 1 | Sept. 13 | Las Vegas Raiders vs. Baltimore Ravens |
| Week 2 | Sept. 20 | Green Bay Packers vs. Detroit Lions |
| Week 3 | Sept. 27 | Dallas Cowboys vs. Philadelphia Eagles |
| Week 4 | Oct. 4 | Los Angeles Chargers vs. Las Vegas Raiders |
| Week 5 | Oct. 11 | Baltimore Ravens vs. Indianapolis Colts |
| Week 6 | Oct. 18 | Tennessee Titans vs. Buffalo Bills |
| Week 7 | Oct. 25 | Seattle Seahawks vs. New Orleans Saints |
| Week 8 | Nov. 1 | Kansas City Chiefs vs. New York Giants |
| Week 9 | Nov. 8 | Pittsburgh Steelers vs. Chicago Bears |
| Week 10 | Nov. 15 | San Francisco 49ers vs. Los Angeles Rams |
| Week 11 | Nov. 22 | Tampa Bay Buccaneers vs. New York Giants |
| Week 12 | Nov. 29 | Washington Football Team vs. Seattle Seahawks |
| Week 13 | Dec. 6 | Buffalo Bills vs. New England Patriots |
| Week 14 | Dec. 13 | Arizona Cardinals vs. Los Angeles Rams |
| Week 15 | Dec. 20 | Chicago Bears vs. Minnesota Vikings |
| Week 16 | Dec. 27 | New Orleans Saints vs. Miami Dolphins |
| Week 17 | Jan. 3 | Pittsburgh Steelers vs. Cleveland Browns |
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